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GLUD1 Rabbit Polyclonal Antibody

CAT: 0992-ER1902-85Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1902-85Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
CAS Number
9007-83-4
Product Name Alternative
AI118167 antibody DHE3_HUMAN antibody EC 1.4.1.3 antibody GDH 1 antibody GDH antibody Gdh-X antibody GDH1 antibody GLUD antibody Glud1 antibody Glud1a antibody Glud1b antibody Gludl antibody Glutamate dehydrogenase (NAD (P)+) antibody Glutamate dehydrogenase 1 antibody Glutamate dehydrogenase 1 mitochondrial antibody Glutamate dehydrogenase 1a antibody Glutamate dehydrogenase 1b antibody Memory-related gene 2 protein antibody MGC127177 antibody MGC132003 antibody MGC80801 antibody MGC93608 antibody mitochondrial antibody MRG-2 antibody
Abbreviation
GLUD1
Swiss Prot
P00367 Human, P26443 Mouse, P10860 Rat
Cellular Locus
Mitochondrion matrix.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human GLUD1 aa 115-164 / 558.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Hela cell lysate, HepG2 cell lysate, rat kidney tissue, human liver tissue, human liver carcinoma tissue, human colon carcinoma tissue, human breast carcinoma tissue, mouse liver tissue, SW620.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 61 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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