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KCNN2 Rabbit Polyclonal Antibody

CAT: 0992-ER1902-41Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1902-41Size:100 µL
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Description
Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, also known as KCNN2, is a protein which in humans is encoded by the KCNN2 gene. KCNN2 is an ion channel protein also known as KCa2.2. Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The KCa2.2 protein is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. KCa2.2 is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This protein is a member of the calcium-activated potassium channel family. Two transcript variants encoding different isoforms have been found for the KCNN2 gene.
CAS Number
9007-83-4
Product Name Alternative
Apamin sensitive small conductance Ca2+ activated potassium antibody Apamin sensitive small conductance Ca2+ activated potassium channel antibody hSK2 antibody KCa2.2 antibody Kcnn2 antibody KCNN2_HUMAN antibody Potassium intermediate/small conductance calcium activated antibody Potassium intermediate/small conductance calcium activated channel subfamily N member 2 antibody SK2 antibody SKCa 2 antibody SKCa2 antibody Small conductance calcium activated potassium channel antibody Small conductance calcium activated potassium channel protein 2 antibody Small conductance calcium-activated potassium channel protein 2 antibody
Abbreviation
Small conductance calcium-activated potassium channel protein 2,SK2,SKCa 2,SKCa2,KCa2.2
Swiss Prot
Q9H2S1 Human, P58390 Mouse, P70604 Rat
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within rat KCNN2 aa 531-580 / 580.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Rat brain tissue lysates, rat brain tissue, rat cerebellar tissue, mouse brain tissue, rat cerebellar tissue, human colon tissue, F9.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 64 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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