CD35 Rabbit Polyclonal Antibody

CAT: 0992-ER1901-82Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-ER1901-82Size:100 µL
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Description
Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages. Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation. Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells.
CAS Number
9007-83-4
Product Name Alternative
C3 binding protein antibody C3b/C4b receptor antibody C3BR antibody C4BR antibody CD 35 antibody CD35 antibody CD35 antigen antibody complement component (3b/4b) receptor 1 (Knops blood group) antibody complement component (3b/4b) receptor 1 including Knops blood group system antibody Complement component receptor 1 antibody Complement receptor 1 antibody Complement receptor type 1 antibody CR 1 antibody CR1 antibody CR1_HUMAN antibody KN antibody Knops blood group antigen antibody
Abbreviation
CR1, C3BR
Swiss Prot
P17927 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human CD35 aa 290-339 / 2,039.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
K562 cell, 293T cell, HL-60 cell.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000;IF-Cell:1:50-1:200;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 224 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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