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IL-2RG Rabbit Polyclonal Antibody

CAT: 0992-HA500318Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500318Size:100 µL
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Description
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as The IL2RG gene provides instructions for making a protein called the common gamma chain. This protein is a component of several different receptors that are involved in immune system function. The receptors span the cell membrane, with one end outside the cell like an antenna and the other end inside to transmit signals to the nucleus. Other proteins attach to these receptors, like a key in a lock, to trigger a series of chemical reactions inside the cell. Receptors containing the common gamma chain are located on the surface of immature blood-forming cells in bone marrow. They partner with other proteins to direct blood-forming cells to form lymphocytes (a type of white blood cell). The receptors also regulate the growth and maturation of several subtypes of lymphocytes: T cells, B cells, and natural killer cells. These cells kill viruses, make antibodies, and help regulate the entire immune system.
CAS Number
9007-83-4
Product Name Alternative
CD132 antibody CD132 antigen antibody CIDX antibody common cytokine receptor gamma chain antibody Cytokine receptor common subunit gamma antibody Gamma C antibody gamma (c) antibody gammaC antibody IL-2 receptor subunit gamma antibody IL-2R gamma chain antibody IL-2R subunit gamma antibody IL-2RG antibody Il2rg antibody IL2RG_HUMAN antibody IMD4 antibody interleukin 2 receptor, gamma antibody Interleukin-2 receptor subunit gamma antibody p64 antibody SCIDX antibody SCIDX1 antibody
Abbreviation
IL2RG
Swiss Prot
P31785 Human, P34902 Mouse,
Cellular Locus
Cell membrane, Cell surface.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human IL-2RG aa 201-250.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Rat brain tissue lysate, mouse brain tissue lysate, SW480 cell lysates, SH-SY5Y, human colon carcinoma tissue, mouse spleen tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IF-Cell: 1:200 ;IHC-P: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 42 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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