Products for Research Use Only

ACY-1 Rabbit Polyclonal Antibody

CAT: 0992-ER1803-75Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-ER1803-75Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene.
CAS Number
9007-83-4
Product Name Alternative
ACY 1 antibody ACY-1 antibody Acy1 antibody ACY1_HUMAN antibody ACY1D antibody ACYLASE antibody Acylase I antibody Aminoacylase 1 antibody Aminoacylase-1 antibody EC 3.5.1.14 antibody epididymis secretory protein Li 5 antibody HEL-S-5 antibody N acyl L amino acid amidohydrolase antibody N-acyl-L-amino-acid amidohydrolase antibody OTTHUMP00000212459 antibody OTTHUMP00000212462 antibody OTTHUMP00000212463 antibody OTTHUMP00000212464 antibody OTTHUMP00000212465 antibody
Abbreviation
ACY-1, ACY1
Swiss Prot
Q03154 Human, Q99JW2 Mouse, Q6AYS7 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human ACY-1 aa 50-250.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Rat kidney tissue lysate, mouse kidney tissue lysate, HT-29, SH-SY-5Y, rat brain tissue, human liver cancer tissue, human kidney tissue, human small intestine tissue, mouse liver tissue.
Concentration
1 mg/mL
Dilution
WB:1:2,000-1:10,000;IF-Cell:1:50-1:200;IHC-P:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 46 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No