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USP14 Rabbit Polyclonal Antibody

CAT: 0992-ER1803-55Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-55Size:100 µL
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Description
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions. Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.
CAS Number
9007-83-4
Product Name Alternative
Deubiquitinating enzyme 14 antibody TGT antibody tRNA guanine transglycosylase 60 kD subunit antibody tRNA guanine transglycosylase antibody Ubiquitin carboxyl terminal hydrolase 14 antibody Ubiquitin carboxyl-terminal hydrolase 14 antibody Ubiquitin specific peptidase 14 antibody Ubiquitin specific processing protease 14 antibody Ubiquitin specific protease 14 antibody Ubiquitin thiolesterase 14 antibody Ubiquitin-specific-processing protease 14 antibody UBP14_HUMAN antibody USP 14 antibody USP14 antibody
Abbreviation
USP14, TGT
Swiss Prot
P54578 Human
Cellular Locus
Plasma membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human USP14 aa 226-408 / 494.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
Daudi cell lysates, SiHa.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 56 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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