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IL12B Rabbit Polyclonal Antibody

CAT: 0992-ER1803-31Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-31Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
CAS Number
9007-83-4
Product Name Alternative
CLMF antibody CLMF p40 antibody CLMF2 antibody Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody IL 12B antibody IL-12 subunit p40 antibody IL-12B antibody IL12 p40 antibody IL12B antibody IL12B_HUMAN antibody IMD28 antibody IMD29 antibody Interleukin 12 beta chain antibody Interleukin 12 p40 antibody Interleukin-12 subunit beta antibody NK cell stimulatory factor chain 2 antibody NKSF antibody NKSF2 antibody
Abbreviation
IL-12B, CLMF p40, NKSF2, IL12B, NKSF2
Swiss Prot
P29460 Human, P43432 Mouse
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within mouse IL12B aa 220-300.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
Hela, Mouse placenta tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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