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LAMP2a Rabbit Polyclonal Antibody

CAT: 0992-ER1802-99Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1802-99Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107A) and LAMP-2 (also designated CD107B) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans Golgi network and are transported intracellularly via a pathway that is distinct from the clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.
CAS Number
9007-83-4
Product Name Alternative
CD107 antigen-like family member B antibody CD107b antibody LAMP 2 antibody Lamp 2a antibody LAMP-2 antibody LAMP2 antibody LAMP2_HUMAN antibody Lysosome-associated membrane glycoprotein 2 antibody Lysosome-associated membrane protein 2 antibody
Abbreviation
LAMP-2, Lysosome-associated membrane protein 2, LAMP2
Swiss Prot
P13473 Human
Cellular Locus
Plasma membrane. Endosome. Lysosome.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within C-terminal human LAMP2a.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Mouse placenta tissue, human prostate tissue, human kidney tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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