Products for Research Use Only

PTP1B Rabbit Polyclonal Antibody

CAT: 0992-ER1802-83Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-ER1802-83Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The phosphorylation of proteins at tyrosine residues has long been recognized as an important regulatory component of signal transduction. This is a reversible process, involving both enzymes that phosphorylate proteins on tyrosine residues as well as a rapidly expanding family of protein tyrosine phosphatases. These latter enzymes bear little resemblance to either the protein serine and protein threonine phosphatases or to the acid and alkaline phosphatases. In most tissues, the major PTPase is a vanadate- and molybdate-sensitive protein. On the basis of sequence analysis, PTP1B (PTPase 1B) expressed in human placenta exhibits similarities both with the common leukocyte antigen (CD45) and with LAR, a homolog of the neural adhesion molecule (NCAM). PTP1B is synthesized as a 435 amino acid precursor protein which is cleaved to generate the active 321 amino acid enzyme.
CAS Number
9007-83-4
Product Name Alternative
PTP1B antibody Non receptor tyrosine phosphatase 1 antibody Protein phosphotyrosylphosphatase 1B antibody Protein tyrosine phosphatase 1B antibody Protein tyrosine phosphatase non receptor type 1 antibody Protein tyrosine phosphatase placental antibody Protein-tyrosine phosphatase 1B antibody PTN1_HUMAN antibody PTP 1B antibody PTP-1B antibody PTPN 1 antibody PTPN1 antibody Tyrosine protein phosphatase non receptor type 1 antibody Tyrosine-protein phosphatase non-receptor type 1 antibody
Abbreviation
PTP-1B, PTPN1, PTP1B
Swiss Prot
P18031 Human
Cellular Locus
Endoplasmic reticulum, Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human PTP1B aa 1-50 / 435.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Hela cell lysate, A431 cell lysate, HUVEC, LOVO, human tonsil tissue, human colon cancer tissue, human kidney tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:200-1:500;IHC-P: 1:50-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 50 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No