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LGR5 Rabbit Polyclonal Antibody

CAT: 0992-ER10708Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER10708Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
CAS Number
9007-83-4
Product Name Alternative
FEX antibody G protein coupled receptor 49 antibody G protein coupled receptor 67 antibody g protein-coupled receptor fex antibody G-protein coupled receptor 49 antibody G-protein coupled receptor 67 antibody G-protein coupled receptor HG38 antibody GPR 49 antibody GPR 67 antibody GPR49 antibody GPR67 antibody GRP 49 antibody GRP49 antibody HG 38 antibody HG38 antibody Leucine rich repeat containing G protein coupled receptor 5 antibody Leucine-rich repeat-containing G-protein coupled receptor 5 antibody LGR 5 antibody LGR5 antibody LGR5_HUMAN antibody MGC117008 antibody Orphan G protein coupled receptor HG38 antibody
Abbreviation
LGR5,GPR49, GPR67
Swiss Prot
O75473 Human, Q9Z1P4 Mouse,
Cellular Locus
Cytoplasm, cell membrane, Golgi apparatus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to Mouse GPR49 / LGR5 alpha / beta aa 1-50 / 907 (ID: Q9Z1P4).
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
Mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, F9 cell lysate, Hela cell lysate, K562 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 100 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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