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Beta-2 Microglobulin Rabbit Polyclonal Antibody

CAT: 0992-0808-2Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-0808-2Size:100 µL
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Description
β2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on almost all cells of the body. β-2-Microglobulin associates with the α heavy chain of MHC and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
CAS Number
9007-83-4
Product Name Alternative
B2M antibody B2MG_HUMAN antibody Beta 2 microglobin antibody Beta 2 microglobulin antibody Beta 2 microglobulin precursor antibody Beta chain of mhc class 1 proteins antibody Beta chain of MHC class I molecules antibody Beta-2-microglobulin form pI 5.3 antibody CDABP0092 antibody Hdcma22p antibody
Abbreviation
B2M
Swiss Prot
P61769 Human
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human Beta-2 Microglobulin aa 21-70.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HL-60 cells.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:200 ;FC: 1:50
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
13 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No