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Perfluorodecanoic acid

CAT: 0804-HY-W269593Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W269593Size:100 mg
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Description
Perfluorodecanoic acid (PFDA) is a perfluoroalkyl substance (PFAS) . Perfluorodecanoic acid induces weight loss and increases liver weight and lipid content in mice. Perfluorodecanoic acid also reduces mRNA expression of the genes encoding IL-1β, IL-18, and cellular inhibitor of apoptosis 2 (cIAP2), as well as caspase-1, -3, and -7 in mouse liver[1][2].
CAS Number
335-76-2
Product Name Alternative
PFDA
UNSPSC
12352211
Hazard Statement
H301, H351, H360, H362
Target
Caspase; Interleukin Related
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Purity
98.21
Solubility
DMSO : 100 mg/mL|Ethanol : 100 mg/mL (ultrasonic)
Smiles
C(=O)(C(C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O
Molecular Formula
C10HF19O2
Molecular Weight
514.08
Precautions
H301, H351, H360, H362
References & Citations
[1]Olson CT, et al. The acute toxicity of perfluorooctanoic and perfluorodecanoic acids in male rats and effects on tissue fatty acids. Toxicol Appl Pharmacol. 1983 Sep 30;70 (3) :362-72. |[2]Harris MW, et al. Developmental toxicity of perfluorodecanoic acid in C57BL/6N mice. Fundam Appl Toxicol. 1989 Apr;12 (3) :442-8.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 1; Caspase 3; Caspase 7; IL-1

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