Products for Research Use Only
RegisterLogin

Masticadienonic acid

CAT: 0804-HY-N8563Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N8563Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Masticadienonic acid is an orally active and selective inhibitor of MAPK (p38, ERK, JNK) and NF-κB pathways and an agonist of the Nrf2 pathway. Masticadienonic acid reduces the release of pro-inflammatory cytokines such as TNFα, IL-1β, and IL-6, restores the expression of intestinal tight junction proteins (ZO-1, occludin), and modulates gut microbiota. Masticadienonic acid is promising for research of inflammatory bowel disease[1].
CAS Number
514-49-8
UNSPSC
12352211
Target
Keap1-Nrf2; NF-κB; p38 MAPK
Related Pathways
MAPK/ERK Pathway; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
C[C@@]12C3=CC[C@](C(C)(C(CC4)=O)C)([H])[C@@]4(C)[C@@]3([H])CC[C@]1([C@](CC2)([H])[C@@H](C)CC/C=C(C)\C(O)=O)C
Molecular Formula
C30H46O3
Molecular Weight
454.68
References & Citations
[1]Cui H, et al. Masticadienonic acid from Chios mastic gum mitigates colitis in mice via modulating inflammatory response, gut barrier integrity and microbiota. Phytomedicine. 2023 Jan;108:154518.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N3313Masticadienolic acid
HY-140589Acid-PEG4-S-PEG4-acid
HY-140112-01Acid-PEG2-SS-PEG2-acid
HY-140113-01Acid-PEG3-SS-PEG3-acid
HY-W096114-01Acid-PEG8-S-S-PEG8-acid
HY-140114-01Acid-PEG4-S-S-PEG4-acid
HY-N8543Gliocladic acid
HY-N17650Salviamarinic acid A
HY-N16388α-Costic acid
HY-N15317-01Phocaecholic acid

Alternative Products

CatalogName
T131480-01Masticadienonic acid
MBS5825192(E)-Masticadienonic acid
GTR19217993-01(E) -Masticadienonic acid
OR1071368-01Acid-apeg6-acid
MBS6083807-01Medronic Acid (Methylenebiphosphonic Acid, Methylenediphosphonic Acid, Methanebisphosphonic Acid, Methanediphosphonic Acid, MDP)
L2500-01Lipoic Acid (Thioctic Acid, (±) -α-Lipoic Acid)
041005Cacodylic Acid (dimethylarsonic acid, dimethylarsinic acid)
MBS641082-01Lipoic Acid (Thioctic Acid, Alpha Lipoic Acid)
275335-01Ethylenediaminediacetic acid dipropionic acid
O8099-01Oxalacetic Acid (Oxaloacetic acid)

Popular Products