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Perfluorododecanoic acid

CAT: 0804-HY-W275295-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W275295-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Perfluorododecanoic acid (PFDoA) is a perfluoroalkyl substance (PFAS) found in lake trout. Perfluorododecanoic acid decreases the viability of PC12 cells. Perfluorododecanoic acid also increases reactive oxygen species (ROS), malondialdehyde (MDA) levels and reduces the mitochondrial membrane potential in PC12 cells[1][2].
CAS Number
307-55-1
Product Name Alternative
PFDoA
UNSPSC
12352211
Hazard Statement
H302+H332, H351, H360, H362, H372
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Metabolic Disease
Purity
95
Solubility
DMSO : 5.83 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C(=O)(C(C(C(C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O
Molecular Formula
C12HF23O2
Molecular Weight
614.10
Precautions
H302+H332, H351, H360, H362, H372
References & Citations
[1]Liu Y, et al. Induction of time-dependent oxidative stress and related transcriptional effects of perfluorododecanoic acid in zebrafish liver. Aquat Toxicol. 2008 Sep 29;89 (4) :242-50. |[2]Furdui VI, et al. Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes. Environ Sci Technol. 2007 Mar 1;41 (5) :1554-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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