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LY 806303

CAT: 0804-HY-117798Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117798Size:1 Each
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Description
LY 806303 is a potent and selective inhibitor of human α-thrombin. LY 806303 specifically acylates Ser-205 within the catalytic triad of α-thrombin on the heavy chain and a key site involved in the enzymatic activity of thrombin. The mechanism of action of LY 806303 as an enzyme inhibitor is through the specific acylation of this catalytic serine residue[1].
CAS Number
149725-15-5
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ly-806303.html
Smiles
O=C(OC)C1=C(C2=C(O1)C3=CC=CC=C3S2)OC(C(C)C)=O
Molecular Formula
C16H14O5S
Molecular Weight
318.34
References & Citations
[1]Characterization of the Interaction between Human a-Thrombin and Methyl 3- (2-Methyl-l-oxopropoxy) [ l]benzothieno[ 3,2-b]furan-2-carboxylate (LY806303) Using Electrospray Mass Spectrometry and Tandem Mass Spectrometry
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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