(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate)

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate)

• CAS Number: 143077-65-0
• UNSPSC Description: (D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate) is an antagonist for Substance P (HY-P0201) and Bombesin (HY-P0195) that has effects on ocular inflammatory responses to antidromic trigeminal nerve stimulation[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/d-arg1-d-pro2-d-trp7-9-l-leu11-substance-p-acetate.html
• Solubility: 10 mM in DMSO
• Smiles: C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CC(C)C)=O)=O)=O)NC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC(=O)[C@@H]5N(C([C@@H](CCCNC(=N)N)N)=O)CCC5)CCCCN)=O)CCC4)CCC(N)=O)=O)CCC(N)=O)=O)C=6C=7C(NC6)=CC=CC7.xC(C)(O)=O
• Molecular Weight: 1497.79 (free base)
• References & Citations: [1]A Mandahl, A Bill, et al. Effects of the substance P antagonist, (D-Arg1, D-Pro2, D-Trp7,9, Leu11)-SP on the miotic response to substance P, antidromic trigeminal nerve stimulation, capsaicin, prostaglandin E1, compound 48/80 and histamine. Acta Physiol Scand. 1984 Jan;120(1):27-35.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported