[D-Pro4,D-Trp7,9] Substance P (4-11)

[D-Pro4,D-Trp7,9] Substance P (4-11)

• CAS Number: 81039-85-2
• UNSPSC Description: [D-Pro4,D-Trp7,9] Substance P (4-11) is a potent antagonist of Substance P (HY-P0201). [D-Pro4,D-Trp7,9] Substance P (4-11) decreases plasma aldosterone (ALDO) concentration[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/d-pro4-d-trp7-9-substance-p-4-11.html
• Solubility: 10 mM in DMSO
• Smiles: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=CC=C3)NC([C@@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@@H]6NCCC6)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 1134.35
• References & Citations: [1]Mizrahi J, et al. Substance P antagonists active in vitro and in vivo. Eur J Pharmacol. 1982 Aug 13;82(1-2):101-5.|[2]Mazzocchi G, et al. Evidence that endogenous substance-P (SP) is involved in the maintenance of the growth and steroidogenic capacity of rat adrenal zona glomerulosa. Neuropeptides. 1995 Jul;29(1):53-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported