[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)

• UNSPSC Description:

  [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP)[1].

• Target Antigen:

  Neurokinin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/d-pro4-d-trp7-9-nle11-substance-p-4-11.html

• Solubility:

  H2O

• Smiles:

  CCCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=CC=C3)NC([C@@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@@H]6NCCC6)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  1116.31

• References & Citations:

  [1]Cathieni M M, et al. Pharmacological Evidence that Gold-Protein-Substance P Complex Activates Neurokinin NK1 Receptors[J]. Cellular Physiology & Biochemistry, 1995, 5(2):85-95.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  89430-34-2