CMIP rabbit pAb

• Background:

  This gene encodes a c-Maf inducing protein that plays a role in T-cell signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

• Description:

  This gene encodes a c-Maf inducing protein that plays a role in T-cell signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],

• Synonyms:

  C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip)

• Gene ID:

  80790

• UniProt:

  Q8IY22

• Cellular Locus:

  Nucleus. Cytoplasm. Isoform 2 is translocated to the nucleus and is specifically recruited during minimal change nephrotic syndrome (MCNS) (PubMed:12939343) (PubMed:15616553). Detected in nuclear and cytoplasmic compartments during MCNS relapse (PubMed:12939343) (PubMed:15616553). Expressed in cytoplasm only during MCNS remission and absent in normal patients (PubMed:12939343)..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human CMIP AA range: 105-155

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB

• Validated Applications:

  WB

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000

• Molecular Weight:

  85kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  85 kD

• Subcellular Location:

  Nucleus . Cytoplasm . Isoform 2 is translocated to the nucleus and is specifically recruited during minimal change nephrotic syndrome (MCNS) (PubMed:12939343) (PubMed:15616553) . Detected in nuclear and cytoplasmic compartments during MCNS relapse (PubMed:12939343) (PubMed:15616553) . Expressed in cytoplasm only during MCNS remission and absent in normal patients (PubMed:12939343) . .

• Other Product Names:

  C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip)

• Gene ID (Human):

  80790

• SwissProt (Human):

  Q8IY22