Anticancer agent 225

• Description:

  Anticancer agent 225 (Comp 51) is a triterpenoic acids analogue which exhibits suppressive effect on elimination of different type of cancer stem cells (CSCs) and increase the ROS level of CSCs. Anticancer agent 225 can be used for cancer research[1].

• UNSPSC:

  12352005

• Target:

  Reactive Oxygen Species (ROS)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-225.html

• Purity:

  97.1

• Solubility:

  10 mM in DMSO

• Smiles:

  COC(C=C1)=CC=C1NC(NCCNC([C@]23[C@](CC(C)(CC3)C)([H])C4=CC[C@@]([C@@]5([C@@](C(C)(C(C(C5)=C)=O)C)([H])CC6)C)([H])[C@]6(C)[C@@]4(CC2)C)=O)=S

• Molecular Formula:

  C41H59N3O3S

• Molecular Weight:

  673.99

• References & Citations:

  [1]Liu X, et al. Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids. J Med Chem. 2018 Dec 13;61 (23) :10814-10833.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2251753-61-2]