CDK7-IN-2

CAT:

804-HY-143587-01

Size:

10 mg

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CAS Number: 2326428-19-5
UNSPSC Description: CDK7-IN-2 is a potent inhibitor of CDK7. CDK7 is implicated in both temporal control of the cell cycle and transcriptional activity. CDK7 is implicated in the transcriptional initiation process by phosphorylation of Rbpl subunit of RNA Polymerase II (RNAPII). CDK7 has the potential for the research of cancer disease, in particular aggressive and hard- to-treat cancers (extracted from patent WO2019099298A1, compound 1)[1].
Target Antigen: CDK
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-Kinase/protease
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/cdk7-in-2.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: O=C(N1CCC(NC2=CC(C)=NC3=C(C(C)C)C=NN23)CC1)O[C@@H]4CN(C(/C=C/CN(C)C)=O)CC4
Molecular Weight: 497.63
References & Citations: [1]David Andrew Coates, et al. Compounds useful for inhibiting cdk7. Patent WO2019099298A1.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-143587-06	CDK7-IN-2
HY-143587-05	CDK7-IN-2
HY-143587-03	CDK7-IN-2
HY-143587-02	CDK7-IN-2
HY-143587-01	CDK7-IN-2
HY-143587-04	CDK7-IN-2
HY-136711	CDK7-IN-2 (hydrochloride hydrate)
HY-153278-02	CDK7-IN-21
HY-169344	CDK7-IN-31
HY-162416	CDK7-IN-27

Cat	Name
T63368-1mg	CDK7-IN-2
T63368-1g	CDK7-IN-2
T63368-5mg	CDK7-IN-2
BA3830-1	CDK7-IN-2
T63368-10mg	CDK7-IN-2
BA3830-5	CDK7-IN-2
T63368-50mg	CDK7-IN-2
BA3830-10	CDK7-IN-2
BA3830-25	CDK7-IN-2
MBS5800250-01	CDK7-IN-2 hydrochloride hydrate