CDK7-IN-2 (hydrochloride hydrate)

CAT:

804-HY-136711

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CAS Number: 2326428-24-2
UNSPSC Description: CDK7-IN-2 hydrochloride hydrate (Example 6) is a potent and selective CDK7 inhibitor. CDK7-IN-2 has potent anti-cancer activity[1][2].
Target Antigen: CDK
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-Kinase/protease
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/cdk7-in-2-hydrochloride-hydrate.html
Solubility: 10 mM in DMSO
Smiles: O=C(N1CCC(NC2=CC(C)=NC3=C(C(C)C)C=NN23)CC1)O[C@@H]4CN(C(/C=C/CN(C)C)=O)CC4.O.Cl
Molecular Weight: 552.11
References & Citations: [1]Georgina P Sava, et al. CDK7 inhibitors as anticancer drugs. Cancer Metastasis Rev. 2020 May 8.|[2]David Andrew Coates, et al. (e)-1-(4-(dimethylamino)but-2-enoyl)pyrrolidin-3-yl 4-((3-isopropyl-5-methylpyrazolo[1,5-a]pyrimidin-7-yl)amino)piperidine-1-carboxylate for inhibiting cdk7, US20200017513A1.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-136711	CDK7-IN-2 (hydrochloride hydrate)
HY-143587-04	CDK7-IN-2
HY-143587-06	CDK7-IN-2
HY-143587-05	CDK7-IN-2
HY-143587-03	CDK7-IN-2
HY-143587-02	CDK7-IN-2
HY-143587-01	CDK7-IN-2
HY-W087937-01	Benzamidine (hydrochloride hydrate)
HY-105064D-07	Zoniporide (hydrochloride hydrate)
HY-105064D-03	Zoniporide (hydrochloride hydrate)

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T39864-5mg	CDK7-IN-2 hydrochloride hydrate
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