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N-acetyldopamine

CAT: 0804-HY-N7493-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7493-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-acetyldopamine is a sepiapterin reductase inhibitor. N-acetyldopamine is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle. N-acetyldopamine can attenuate LPS-stimulated TNF-α production and superoxide production in THP-1 cells[1][2].
CAS Number
2494-12-4
Product Name Alternative
NADA
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Reactive Oxygen Species (ROS) ; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n-acetyldopamine.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(NCCC1=CC=C(O)C(O)=C1)=O
Molecular Formula
C10H13NO3
Molecular Weight
195.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Hanine Barek, et al. Unraveling Complex Molecular Transformations of N-β-alanyldopamine That Account for Brown Coloration of Insect Cuticle. Rapid Commun Mass Spectrom. 2017 Aug 30;31 (16) :1363-1373.|[2]Perianayagam, M. C., et al., (2005) . Immune-modulating effects of melatonin, N-acetylserotonin, and N-acetyldopamine. Annals of the New York Academy of Sciences, 1053, 386–393.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Phase 4
Isoform
Human Endogenous Metabolite

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