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(E/Z) -OSM-SMI-10B

CAT: 0804-HY-148692ASize: 1 EachDry Ice: NoHazardous: No
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Description
(E/Z) -OSM-SMI-10B a derivative of OSM-SMI-10. (E/Z) -OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M) [1].
CAS Number
2502294-55-3
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-osm-smi-10b.html
Smiles
O=C(O)/C=C/C1=CC(C2=CC=C(OCO3)C3=C2)=C(C4=CC=C(OCO5)C5=C4)O1
Molecular Formula
C21H14O7
Molecular Weight
378.33
References & Citations
[1]Mass OA, et al. Bioactive recombinant human oncostatin M for NMR-based screening in drug discovery. Sci Rep. 2021 Aug 10;11 (1) :16174.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Osm-smi-10B
CAS Number2502294-55-3
PubChem CID155202044
IUPAC Name(E)-3-[4,5-bis(1,3-benzodioxol-5-yl)furan-2-yl]prop-2-enoic acid
Molecular FormulaC21H14O7
Molecular Weight378.3
XLogP3.9
Topological Polar Surface Area87.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Heavy Atom Count28
Formal Charge0
Complexity608
SMILES
C1OC2=C(O1)C=C(C=C2)C3=C(OC(=C3)/C=C/C(=O)O)C4=CC5=C(C=C4)OCO5
InChI
InChI=1S/C21H14O7/c22-20(23)6-3-14-9-15(12-1-4-16-18(7-12)26-10-24-16)21(28-14)13-2-5-17-19(8-13)27-11-25-17/h1-9H,10-11H2,(H,22,23)/b6-3+
InChIKey
KCTZPNCRBRJVBH-ZZXKWVIFSA-N
Chemical Structure
2D Structure
2D structure of Osm-smi-10B
CAS: 2502294-55-3
CID: 155202044
Formula: C21H14O7
MW: 378.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight378.3
XLogP33.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass378.07395278
Monoisotopic Mass378.07395278
Topological Polar Surface Area87.4 Ų
Heavy Atom Count28
Formal Charge0
Complexity608
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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