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TG2-179-1

CAT:
804-HY-158774-01
Size:
1 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
TG2-179-1 - image 1

TG2-179-1

  • CAS Number: 1135023-19-6
  • UNSPSC Description: TG2-179-1 is a potent BAP1 inhibitor. TG2-179-1 inhibits the domain-containing deubiquitinase (DUB) activity of BAP1 by covalently binding to its active site. TG2-179-1 exerts cytotoxic activity, leading to defective replication and increased apoptosis. TG2-179-1 has the potential for colon cancer research[1].
  • Target Antigen: Apoptosis
  • Type: Reference compound
  • Related Pathways: Apoptosis
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/tg2-179-1.html
  • Solubility: DMF : 2 mg/mL (ultrasonic;warming)
  • Smiles: N#CC1=C(NC(CSC2=NN=C(C3=CC=C(Cl)C=C3)O2)=O)SC(C)=C1C4=CC=C(C=C4)F
  • Molecular Weight: 484.95
  • References & Citations: [1]Minhwa Kang, et al. Targeting BAP1 with small compound inhibitor for colon cancer treatment. Sci Rep. 2023 Feb 8;13(1):2264.
  • Shipping Conditions: Blue Ice
  • Clinical Information: No Development Reported