CCL4/MIP-1 beta Recombinant Rabbit Monoclonal Antibody [JE33-21]

CCL4/MIP-1 beta Recombinant Rabbit Monoclonal Antibody [JE33-21]

• Description: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B.
• Product Name Alternative: MIP 1 beta antibody Secreted protein G 26 antibody ACT 2 antibody ACT-2 antibody ACT2 antibody AT744.1 antibody AT744.2 antibody C C motif chemokine 4 antibody C C motif chemokine 4 like antibody C C motif chemokine ligand 4 like 1 antibody C C motif chemokine ligand 4 like 2 antibody CC chemokine ligand 4 antibody CC chemokine ligand 4L1 antibody CC chemokine ligand 4L1d2 antibody CC chemokine ligand 4L2 antibody CCL4 antibody CCL4_HUMAN antibody ccl4l 1 antibody CCL4L antibody CCL4L1 antibody Chemokine (C C motif) ligand 4 antibody Chemokine (C C motif) ligand 4 like 1 antibody Chemokine (C C motif) ligand 4 like 1, telomeric antibody Chemokine (C C motif) ligand 4 like 2 antibody Chemokine CC Motif Ligand 4 antibody G 26 antibody G 26 T lymphocyte secreted protein antibody G-26 T-lymphocyte-secreted protein antibody HC21 antibody Immune activation 2 antibody LAG 1 antibody LAG-1 antibody LAG1 antibody Lymphocyte activation gene 1 antibody Lymphocyte activation gene 1 protein antibody Macrophage inflammatory protein 1 beta antibody Macrophage inflammatory protein 1-beta antibody Macrophage inflammatory protein 1b2 antibody MGC104418 antibody MGC126025 antibody MGC126026 antibody MIP-1-beta antibody MIP-1-beta (1-69) antibody MIP-1-beta (3-69) antibody MIP1 beta antibody MIP1B antibody MIP1B1 antibody Monocyte adherence induced protein 5 alpha antibody PAT 744 antibody Protein H400 antibody SCYA2 antibody SCYA4 antibody SCYA4L antibody SCYA4L1 antibody SCYA4L2 antibody SCYQ4L2 antibody Secreted protein G 26 antibody Secreted protein G26 antibody SIS gamma antibody SIS-gamma antibody Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody Small inducible cytokine A4 antibody small inducible cytokine A4-like antibody Small-inducible cytokine A4 antibody T cell activation protein 2 antibody T-cell activation protein 2 antibody
• Abbreviation: C-C motif chemokine 4 G-26 T-lymphocyte-secreted protein HC21 Lymphocyte activation gene 1 protein (LAG-1) MIP-1-beta (1-69) Macrophage inflammatory protein 1-beta (MIP-1-beta) PAT 744 Protein H400 SIS-gamma Small-inducible cytokine A4 T-cell activation protein 2 (ACT-2) CCL4 LAG1, MIP1B, SCYA4
• CAS Number: 9000-83-3
• Swiss Prot: P13236 Human, Q8NHW4 Human, P14097 Mouse
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within Human CCL4/MIP-1 beta aa 1-50 / 92.
• Isotype: IgG
• Clone: JE33-21
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB
• Positive Control: THP-1 treated with 100nM TPA overnight then add 100ng/mL LPS for 7 hours then add 1μg/mL BFA for 3 hours cell lysate, RAW264.7 treated with 100nM TPA overnight then add 100ng/mL LPS for 7 hours then add 1μg/mL BFA for 3 hours cell lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 12 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes