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AGN 190727

CAT: 0804-HY-118364Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118364Size:1 Each
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Description
AGN 190727 is a structural isomer of AGN 190121 and has no activating effect on RAR/RXR. AGN 190121 is a RAR-specific agonist that causes a dose-dependent increase in serum triglycerides, leading to hypertriglyceridemia.
CAS Number
115503-91-8
UNSPSC
12352005
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/agn-190727.html
Smiles
OC(C1=CC=CC(C#C/C=C/C2=C(C)CCCC2(C)C)=C1)=O
Molecular Formula
C20H22O2
Molecular Weight
294.39
References & Citations
[1]Retinoid-Induced Hypertriglyceridemia in Rats Is Mediated by Retinoic Acid Receptors
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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