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AGN 205327

CAT: 0804-HY-16685Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16685Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR. IC50 value: 3766/734/32 nM for RARα/β/γ Target: RAR agonist
CAS Number
2070018-29-8
UNSPSC
12352005
Target
Autophagy; RAR/RXR
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/agn-205327.html
Solubility
10 mM in DMSO
Smiles
CC1(C)CCC(C)(C)C2=C1C=CC(/C(C3=CC4=CC(C(O)=O)=CC=C4N3)=N\O)=C2
Molecular Formula
C24H26N2O3
Molecular Weight
390.47
References & Citations
[1]Preferential binding of synthetic retinoid analogs to subtypes of RAR.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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