AGN 205327

• Description:

  AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR. IC50 value: 3766/734/32 nM for RARα/β/γ Target: RAR agonist

• UNSPSC:

  12352005

• Target:

  Autophagy; RAR/RXR

• Type:

  Reference compound

• Related Pathways:

  Autophagy; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/agn-205327.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1(C)CCC(C)(C)C2=C1C=CC(/C(C3=CC4=CC(C(O)=O)=CC=C4N3)=N\O)=C2

• Molecular Formula:

  C24H26N2O3

• Molecular Weight:

  390.47

• References & Citations:

  [1]Preferential binding of synthetic retinoid analogs to subtypes of RAR.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2070018-29-8]