Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-88] - BSA and Azide free (Detector)

Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-88] - BSA and Azide free (Detector)

• Description: Subunit beta of interleukin 12 (also known as IL-12B, natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor p40, or interleukin-12 subunit p40) is a protein subunit that in humans is encoded by the IL12B gene. IL-12B is a common subunit of interleukin 12 and interleukin 23. This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kDa cytokine receptor like subunit encoded by this gene, and a 35 kDa subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.
• Product Name Alternative: CLMF antibody CLMF p40 antibody CLMF2 antibody Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody IL 12 subunit p40 antibody IL 12B antibody IL-12 subunit p40 antibody IL-12B antibody IL12 p40 antibody IL12 subunit p40 antibody IL12B antibody IL12B_HUMAN antibody interleukin 12 beta chain antibody Interleukin 12 p40 antibody Interleukin 12 subunit beta antibody Interleukin 12B antibody Interleukin-12 subunit beta antibody natural killer cell stimulatory factor 40 kD subunit antibody NK cell stimulatory factor chain 2 antibody NKSF antibody NKSF2 antibody p40 antibody
• Abbreviation: Interleukin-12 subunit beta IL-12B Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40) IL-12 subunit p40 Il12b
• CAS Number: 9000-83-3
• Swiss Prot: P43432 Mouse
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Mouse
• Immunogen: Recombinant protein within Mouse IL-12B (aa 23-335)-GSGSSRGGSGSGGSGGGGSK-IL-12A (aa 23-215).
• Isotype: IgG
• Clone: PSH04-88
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: ELISA (Det)
• Positive Control: Recombinant mouse IL-12p40 protein (HA210890).
• Concentration: 1 mg/mL
• Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH04-85] to Mouse IL-12p40 (Capture) (HA722191) and recombinant standard Mouse IL-12p40 protein (HA210890). The reference range value is 37-3000pg/ml.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4).
• Molecular Weight: Predicted band size: 38 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes