Mouse anti-Human IgG Recombinant Mouse Monoclonal Antibody [A5D12-R]

Mouse anti-Human IgG Recombinant Mouse Monoclonal Antibody [A5D12-R]

• Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V- (D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
• Product Name Alternative: FLJ39988 antibody FLJ40036 antibody FLJ40253 antibody FLJ40587 antibody FLJ40789 antibody FLJ40834 antibody G1m marker antibody G2m marker antibody G3m marker antibody G4m marker antibody HDC antibody Heavy chain disease protein antibody Human immunglobulin G antibody Ig gamma 1 chain C region antibody Ig gamma 2 chain C region antibody Ig gamma 3 chain C region antibody Ig gamma 4 chain C region antibody IgG heavy chain locus antibody IGHG 1 antibody IGHG 2 antibody IGHG 3 antibody IGHG 4 antibody IGHG1 antibody IGHG2 antibody IGHG3 antibody IGHG4 antibody Immunoglobulin Gm1 antibody Immunoglobulin Gm3 antibody Immunoglobulin Gm4 antibody immunoglobulin heavy constant gamma 1 (G1m marker) antibody Immunoglobulin heavy constant gamma 1 antibody immunoglobulin heavy constant gamma 2 (G2m marker) antibody Immunoglobulin heavy constant gamma 2 antibody immunoglobulin heavy constant gamma 3 (G3m marker) antibody Immunoglobulin heavy constant gamma 3 antibody immunoglobulin heavy constant gamma 4 (G4m marker) antibody Immunoglobulin heavy constant gamma 4 antibody MGC117419 antibody MGC45809 antibody
• CAS Number: 9000-83-3
• Swiss Prot: P01857 Human, P01859 Human, P01860 Human, P01861 Human
• Cellular Locus: Cell Membrane and Secreted.
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Full length native protein corresponding to Human IgG.
• Isotype: IgG1
• Clone: A5D12-R
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: WB, ELISA
• Positive Control: Recombinant human IgG protein.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;ELISA: 1:1,000-1:20,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4).
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes