Recombinant AMPK Complex (A2+B2+G2) Protein

• Description:

  Recombinant AMPK Complex (A2+B2+G2) Protein_x000D_ Catalog number: B2017549_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 20 µg_x000D_ Molecular Weight or Concentration: 63.7 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: N/A_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Moon S, Han D, Kim Y, Jin J, Ho WK, Kim Y. Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry Sci Rep. 2014 Mar 14;4:4376._x000D_ 2: Rajamohan F, Reyes AR, Frisbie RK, Hoth LR, Sahasrabudhe P, Magyar R, Landro JA, Withka JM, Caspers NL, Calabrese MF, Ward J, Kurumbail RG. Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators Biochem J. 2016 Mar 1;473(5):581-92._x000D_ 3: Shay AE, Diwakar BT, Guan BJ, Narayan V, Urban JF Jr, Prabhu KS. IL-4 up-regulates cyclooxygenase-1 expression in macrophages J Biol Chem. 2017 Sep 1;292(35):14544-14555._x000D_ 4: Pelosse M, Cottet-Rousselle C, Grichine A, Berger I, Schlattner U. Genetically Encoded Fluorescent Biosensors to Explore AMPK Signaling and Energy Metabolism Exp Suppl. 2016;107:491-523._x000D_ 5: Hubbard JA, Xiao B, Wilson JR. Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (α1β1γ1) Methods Mol Biol. 2018;1732:1-14._x000D_ 6: Oakhill JS, Scott JW, Dite TA. Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells Methods Mol Biol. 2018;1732:159-169._x000D_ 7: Zhang D, Tang B, Xie X, Xiao YF, Yang SM, Zhang JW. The interplay between DNA repair and autophagy in cancer therapy Cancer Biol Ther. 2015;16(7):1005-13._x000D_ 8: Scott JW, Norman DG, Hawley SA, Kontogiannis L, Hardie DG. Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate J Mol Biol. 2002 Mar 22;317(2):309-23._x000D_ 9: Woods A, Vertommen D, Neumann D, Turk R, Bayliss J, Schlattner U, Wallimann T, Carling D, Rider MH. Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis J Biol Chem. 2003 Aug 1;278(31):28434-42._x000D_ 10: Willows R, Navaratnam N, Lima A, Read J, Carling D. Effect of different γ-subunit isoforms on the regulation of AMPK Biochem J. 2017 May 9;474(10):1741-1754. _x000D_ _x000D_ Products Related to Recombinant AMPK Complex (A2+B2+G2) Protein can be found at Proteins

• Short Description:

  Catalog Number: B2017549 (20 µg)_x000D_ Recombinant AMPK Complex (A2+B2+G2) Protein is a protein complex composed of three subunits: α (A), β (B), and γ (G). AMP-activated protein kinase (AMPK) is a key regulator of cellular energy homeostasis and is involved in various metabolic processes. The A subunit is the catalytic subunit, the B subunit is involved in regulating the activity of the complex, and the G subunit is responsible for sensing cellular energy levels. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3