Human Recombinant AMPK Complex (α1, β1, and Œ≥1 subunits)

• Description:

  Human Recombinant AMPK Complex (α1, β1, and γ1 subunits)_x000D_ Catalog number: B2017060_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5 µg_x000D_ Molecular Weight or Concentration: ~146 kDa complex (α1: 65 kDa; β1: 38 kDa; γ1: 31 kDa)_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: AMPK Subunit α-1, MGC33776, MGC57364, PRKAA1, AMPK Subunit β-1, HAMPKb, MGC17785, PRKAB1, AMPK Subunit γ-1, AMPKG, MGC8666, PRKAG1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Jensen TE, Ross FA, Kleinert M, Sylow L, Knudsen JR, Gowans GJ, Hardie DG, Richter EA. PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain Biochem J. 2015 May 1;467(3):461-72._x000D_ 2: Iseli TJ, Walter M, van Denderen BJ, Katsis F, Witters LA, Kemp BE, Michell BJ, Stapleton D. AMP-activated protein kinase beta subunit tethers alpha and gamma subunits via its C-terminal sequence (186-270) J Biol Chem. 2005 Apr 8;280(14):13395-400._x000D_ 3: Ghavami S, Shojaei S, Yeganeh B, Ande SR, Jangamreddy JR, Mehrpour M, Christoffersson J, Chaabane W, Moghadam AR, Kashani HH, Hashemi M, Owji AA, Łos MJ. Autophagy and apoptosis dysfunction in neurodegenerative disorders Prog Neurobiol. 2014 Jan;112:24-49._x000D_ 4: Ono H, Suzuki N, Kanno SI, Kawahara G, Izumi R, Takahashi T, Kitajima Y, Osana S, Nakamura N, Akiyama T, Ikeda K, Shijo T, Mitsuzawa S, Nagatomi R, Araki N, Yasui A, Warita H, Hayashi YK, Miyake K, Aoki M. AMPK Complex Activation Promotes Sarcolemmal Repair in Dysferlinopathy Mol Ther. 2020 Apr 8;28(4):1133-1153._x000D_ 5: Wu H, Liu B, Chen Z, Li G, Zhang Z. MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of gastric cancer Cell Death Dis. 2020 Apr 16;11(4):233._x000D_ 6: Rajamohan F, Harris MS, Frisbie RK, Hoth LR, Geoghegan KF, Valentine JJ, Reyes AR, Landro JA, Qiu X, Kurumbail RG. Escherichia coli expression, purification and characterization of functional full-length recombinant alpha2beta2gamma3 heterotrimeric complex of human AMP-activated protein kinase Protein Expr Purif. 2010 Oct;73(2):189-97._x000D_ 7: Hu X, Xiao Y, Sun J, Ji B, Luo S, Wu B, Zheng C, Wang P, Xu F, Cheng K, Hua H, Li D. New possible silver lining for pancreatic cancer therapy: Hydrogen sulfide and its donors Acta Pharm Sin B. 2021 May;11(5):1148-1157._x000D_ 8: Gerner L, Munack S, Temmerman K, Lawrence-Dörner AM, Besir H, Wilmanns M, Jensen JK, Thiede B, Mills IG, Morth JP. Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli Data Brief. 2016 Jun 29;8:733-40._x000D_ 9: Wu C, Chen Y, Zhou P, Hu Z. Recombinant human angiotensin-converting enzyme 2 plays a protective role in mice with sepsis-induced cardiac dysfunction through multiple signaling pathways dependent on converting angiotensin II to angiotensin 1-7 Ann Transl Med. 2023 Jan 15;11(1):13._x000D_ 10: Zhang YL, Guo H, Zhang CS, Lin SY, Yin Z, Peng Y, Luo H, Shi Y, Lian G, Zhang C, Li M, Ye Z, Ye J, Han J, Li P, Wu JW, Lin SC. AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation Cell Metab. 2013 Oct 1;18(4):546-55. _x000D_ _x000D_ Products Related to Human Recombinant AMPK Complex (α1, β1, and γ1 subunits) can be found at Proteins

• Short Description:

  Catalog Number: B2017060 (5 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3