BTT-266

CAT: 0804-HY-115597-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-115597-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
BTT-266 is an antagonist forcalcium channel, through suppression of the CaVα1-AID-CaVβ3 interaction, with a Ki of 1.4 μM. BTT-266 modulates the activation of voltage-dependent CaV2.2. BTT-266 exhibits analgesic efficacy against neuropathic pain in rats model[1].
CAS Number
[2413939-89-4]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/btt-266.html
Purity
98.90
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC(C(N2N=C(CC2C3=CN(C4=CC=CC=C4)N=C3C5=CC=C(C)C=C5)C6=CC=C(OC)C=C6)=O)=C1)O
Molecular Formula
C34H28N4O4
Molecular Weight
556.61
References & Citations
[1]Chen X, et al., Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking. Proc Natl Acad Sci U S A. 2018 Nov 6;115 (45) :E10566-E10575.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-177331BTT-3034
HY-110112-01BTT-3033
HY-111560-01IQM-266
HY-172924NLX-266
HY-155555SCAL-266
HY-133020-01ARD-266
HY-W953170CRBN ligand-266
HY-D0588Acid red 266
HY-D0549Pigment red 266
HY-173040Anticancer agent 266

Alternative Products

CatalogName
MF-0012252-01BTT-266
M34197-01BTT-3033
TRC-B689365-500MGBTT 3033
M17024-01BTT-369
A17200-10BTT-3033 10mg
A17200-5BTT-3033 5mg
A17200-25BTT-3033 25mg
A17200-50BTT-3033 50mg
A17200-100BTT-3033 100mg
G2050-500MLBTT Electrophoresis Buffer (25x)

Popular Products