L-Ascorbic acid (GMP)

L-Ascorbic acid (GMP)

• CAS Number: 50-81-7
• UNSPSC Description: L-Ascorbic acid (L-Ascorbate) (GMP) is L-Ascorbic acid (HY-B0166) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. L-Ascorbic acid is an inhibitor of Cav 3.2 channels[1].
• Target Antigen: Apoptosis; Calcium Channel; Endogenous Metabolite; Reactive Oxygen Species
• Type: GMP Small Molecules
• Related Pathways: Apoptosis;Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB
• Field of Research: Cancer; Metabolic Disease; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/l-ascorbic-acid-gmp.html
• Solubility: 10 mM in DMSO
• Smiles: OC([C@@]1([H])[C@H](CO)O)=C(O)C(O1)=O
• Molecular Weight: 176.12
• References & Citations: [1]Barlian A, et al. Chondrogenic differentiation of Wharton's Jelly mesenchymal stem cells on silk spidroin-fibroin mix scaffold supplemented with L-ascorbic acid and platelet rich plasma. Sci Rep. 2020 Nov 10;10(1):19449.|[2]Mekala NK, et al. Enhanced proliferation and osteogenic differentiation of human umbilical cord blood stem cells by L-ascorbic acid, in vitro. Curr Stem Cell Res Ther. 2013 Mar;8(2):156-62.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: Phase 2