Protriptyline (N-methyl-d3) (hydrochloride)

Protriptyline (N-methyl-d3) (hydrochloride)

• CAS Number: 1435934-21-6
• UNSPSC Description: Protriptyline (N-methyl-d3) (hydrochloride) is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect[1].
• Target Antigen: Cholinesterase (ChE); Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Neuronal Signaling;Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: C(CCNC([2H])([2H])[2H])C1C=2C(C=CC=3C1=CC=CC3)=CC=CC2.Cl
• Molecular Weight: 266.40
• References & Citations: [1]Hudgel DW. Pharmacologic treatment of obstructive sleep apnea. J Lab Clin Med. 1995;126(1):13-18.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported