Lanepitant (dihydrochloride)

• UNSPSC Description:

  Lanepitant dihydrochloride (LY303870 dihydrochloride) is a non-peptide neurokinin-1 receptor antagonist. Lanepitant dihydrochloride has analgesic and anti-inflammatory activities[1][2].

• Target Antigen:

  Neurokinin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/lanepitant-dihydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC(C=CC=C1)=C1CN(C(C)=O)C[C@H](NC(CN2CCC(N3CCCCC3)CC2)=O)CC4=CNC5=C4C=CC=C5.Cl.Cl

• Molecular Weight:

  632.66

• References & Citations:

  [1]Goldstein DJ, et al. Lanepitant, an NK-1 antagonist, in migraine prevention. Cephalalgia. 2001 Mar;21(2):102-6.|[2]Goldstein DJ, et al. Study of the analgesic effect of lanepitant in patients with osteoarthritis pain. Clin Pharmacol Ther. 2000 Apr;67(4):419-26.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  170508-05-1