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Indisetron (dihydrochloride)

CAT: 0804-HY-109543ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-109543ASize:1 Each
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Description
Indisetron dihydrochloride is a 5-HT3 receptor antagonist with anti-emetic activity.
CAS Number
160472-97-9
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/indisetron-dihydrochloride.html
Solubility
10 mM in DMSO
Smiles
CN1C[C@@H]2N(C)[C@H](C1)C[C@@H](C2)NC(C3=NNC4=C3C=CC=C4)=O.Cl.Cl
Molecular Formula
C17H25Cl2N5O
Molecular Weight
386.32
References & Citations
[1]Nakatsumi H, et al. Optimal dose period for indisetron tablets for preventing chemotherapy-induced nausea and vomiting with modified FOLFOX6: a randomized pilot study. Chemotherapy. 2012;58 (6) :439-44.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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