Naspm (trihydrochloride)
CAT:
804-HY-12506A-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Naspm (trihydrochloride)
- Alternative Name: 1-Naphthylacetyl spermine trihydrochloride
- CAS Number: 1049731-36-3
- UNSPSC Description: Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
- Target Antigen: iGluR
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/Naspm-trihydrochloride.html
- Purity: 98.50
- Solubility: DMSO : 6.4 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
- Smiles: [H]Cl.[H]Cl.[H]Cl.O=C(NCCCNCCCCNCCCN)CC1=C2C=CC=CC2=CC=C1
- Molecular Weight: 479.91
- References & Citations: [1]Koike M, et al. Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci Res. 1997 Sep;29(1):27-36.Cell Rep. 2020 Nov 10;33(6):108369. |Cell Rep. 2023 Dec 3;42(12):113551.|iScience. 2023 Mar.|J Headache Pain. 2022 Aug 10;23(1):98.|Neurobiol Dis. 2024 Mar 8:106471.|Neuroscience. 2021 Sep 9;S0306-4522(21)00454-1.|Toxicol In Vitro. 2017 Oct;44:57-65.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported