RC-106

• Description :

  RC-106 is a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator with anticancer activity. RC-106 has antiproliferative activity against cancer cells including glioblastoma (GB) and multiple myeloma (MM) [1].

• UNSPSC :

  12352005

• Target :

  Proteasome; Sigma Receptor

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/rc-106.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C/C(C1=CC2=C(C=CC=C2)C=C1)=C\CN3CCC(CC3)CC4=CC=CC=C4

• Molecular Formula :

  C26H29N

• Molecular Weight :

  355.52

• References & Citations :

  [1]Listro R, et al. Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E) -1- (3-Arylbut-2-en-1-yl) -4- (Substituted) Piperazine Derivatives as Potential Anticancer Agents. Front Chem. 2020 Jun 30;8:495.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1346216-50-9]