Products for Research Use Only
RegisterLogin

ABCG2 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335122-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18335122-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Product Name Alternative
ATP-binding cassette sub-family G member 2; Urate exporter; CD338; ABCP; BCRP; BCRP1; MXR1
UniProt
Q9UNQ0
Reactivity
Human
Immunogen
A synthesized peptide derived from human ABCG2
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q9UNQ0

Broad substrate specificity ATP-binding cassette transporter ABCG2

ABCG2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UNQ0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ABCG2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
7.6.2.-, 7.6.2.2
Processing
—
Secondary accessions
A0A1W3, A8K1T5, O95374, Q4W5I3, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneMembraneMitochondrion

PTM

Disulfide bondGlycoproteinPhosphoprotein

Biological process

Lipid transportTransport

Molecular function

Translocase

Domain

TransmembraneTransmembrane helix

Related Products

CatalogName
GTR18335749-01CD44 Rabbit mAb [KD Validated] Antibody
GTR18335689-01STAT1 Rabbit mAb [KD Validated] Antibody
GTR18335657-01Smad2 Rabbit mAb [KD Validated] Antibody
GTR18335543-01Tuberin Rabbit mAb [KD Validated] Antibody
GTR18335516-01Chk2 Rabbit mAb [KD Validated] Antibody
GTR18335515-01GAP43 Rabbit mAb [KD Validated] Antibody
GTR18335482-01IRAK3 Rabbit mAb [KD Validated] Antibody
GTR18335428-01ADIPOR1 Rabbit mAb [KD Validated] Antibody
GTR18335262-01HDAC4 Rabbit mAb [KD Validated] Antibody
GTR18335231-01Raf1 Rabbit mAb [KD Validated] Antibody

Alternative Products

CatalogName
E46F61391ABCG2 Rabbit Monoclonal Antibody [KD Validated]
A23066[KD Validated] ABCG2 Rabbit pAb
BS78336[KO Validated] ABCG2 polyclonal antibody
AGI1189-100KD-Validated Anti-ABCG2 Rabbit Monoclonal Antibody
HY-P80002-01ABCG2 Antibody (YA648, Rabbit)
APRab00376-01ABCG2 Rabbit Polyclonal Antibody
A03466-100ABCG2 Antibody, mAb, Rabbit
TA590616Rabbit Polyclonal ABCG2 Antibody
SLM-52821R-01Rabbit Anti-ABCG2 antibody
TA422924ABCG2 Rabbit Monoclonal Antibody

Popular Products