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GAP43 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335515-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18335515-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This protein is associated with nerve growth. It is a major component of the motile growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction., , , , ,1, ,1,1,1,0,1,1701055481,0,0,0,0,0,0,0,1701055481,0, -1, -1,0,0 323585,57,58918, JAM1 Rabbit mAb,0,10, JAM1-Rabbit-mAb, JAM1 Rabbit mAb, ,0,50ul,249,249,0,0,0,58, ABWAY, CY5635, CY5635,0,0,0, Yes, Rabbit Monoclonal Antibody, "Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Product Name Alternative
GAP43, Axonal membrane protein GAP-43, B-50, Growth associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46, GAP-43, Protein F1
UniProt
P17677
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human GAP43
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Neuroscience
Purification
Affinity-chromatography
Dilution
WB 1:10000~1:50000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:20
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P17677

Neuromodulin

NEUM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17677
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GAP43
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K0Y4
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Calmodulin-bindingDevelopmental protein

Cellular component

Cell membraneCell projectionCytoplasmMembraneSynapse

Biological process

DifferentiationGrowth regulationNeurogenesis

PTM

LipoproteinPalmitatePhosphoprotein

Technical term

Proteomics identificationReference proteome

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