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HLTF Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334432-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334432-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity) .
Product Name Alternative
HIP116; HIP116A; HLTF 1; Hltf; HLTF1; p113; RNF80; SMARC A3; SMARCA 3; SMARCA3; SNF2L3; ZBU1
UniProt
Q14527
Reactivity
Human, Rat
Immunogen
A synthesized peptide derived from human HLTF
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q14527

DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF

HLTF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14527
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HLTF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27, 3.6.4.-
Processing
—
Secondary accessions
D3DNH3, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorChromatin regulatorDNA-bindingHydrolaseMultifunctional enzymeTransferase

Coding sequence diversity

Alternative initiation

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Cellular component

ChromosomeNucleus

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Biological process

TranscriptionUbl conjugation pathway

Domain

Zinc-finger

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