Pomalidomide-PEG3-C2-NH2
CAT:
804-HY-128716-02
Size:
2 g
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Pomalidomide-PEG3-C2-NH2
- Product Name Alternative: Cereblon Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 30
- CAS Number: 2093416-31-8
- UNSPSC Description: Pomalidomide-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
- Target Antigen: E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-30.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCN)=O
- Molecular Weight: 448.47
- References & Citations: [1]Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported