BRD1, GST-tag Recombinant

• Description:

  BRD1, GST-tag Recombinant_x000D_ Catalog number: B2019174_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 μg_x000D_ Molecular Weight or Concentration: 40 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: ˆ’80°C_x000D_ Keywords: Bromodomain containing 1, BRD1, BRL, BRD-1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Tian J, Wang C, Xia J, Wu L, Xu G, Wu W, Li D, Qin W, Han X, Chen Q, Jin W, Tian F. Teosinte ligule allele narrows plant architecture and enhances high-density maize yields Science. 2019 Aug 16;365(6454):658-664._x000D_ 2: Rajkumar AP, Qvist P, Donskov JG, Lazarus R, Pallesen J, Nava N, Winther G, Liebenberg N, Cour SH, Paternoster V, Fryland T, Palmfeldt J, Fejgin K, Mørk A, Nyegaard M, Pakkenberg B, Didriksen M, Nyengaard JR, Wegener G, Mors O, Christensen JH, Børglum AD. Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice Transl Psychiatry. 2020 Jul 17;10(1):239._x000D_ 3: Paternoster V, Cömert C, Kirk LS, la Cour SH, Fryland T, Fernandez-Guerra P, Stougaard M, Nyengaard JR, Qvist P, Bross P, Børglum AD, Christensen JH. The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation Transl Psychiatry. 2022 Aug 8;12(1):319._x000D_ 4: Wan C, Keany MP, Dong H, Al-Alem LF, Pandya UM, Lazo S, Boehnke K, Lynch KN, Xu R, Zarrella DT, Gu S, Cejas P, Lim K, Long HW, Elias KM, Horowitz NS, Feltmate CM, Muto MG, Worley MJ Jr, Berkowitz RS, Matulonis UA, Nucci MR, Crum CP, Rueda BR, Brown M, Liu XS, Hill SJ. Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer Cancer Res. 2021 Jan 1;81(1):158-173._x000D_ 5: Cai QQ, Dong YW, Qi B, Shao XT, Wang R, Chen ZY, He BM, Wu XZ. BRD1-Mediated Acetylation Promotes Integrin αV Gene Expression Via Interaction with Sulfatide Mol Cancer Res. 2018 Apr;16(4):610-622._x000D_ 6: Li Z, Wang J, Ji Y, Song F. Expression Characteristics and Clinical Correlations of BRD1 in Colorectal Cancer Samples Technol Cancer Res Treat. 2021 Jan-Dec;20:15330338211039678._x000D_ 7: Klein K, Kato M, Frank-Bertoncelj M, Kolling C, Ciurea A, Gay S, Ospelt C. Evaluating the bromodomain protein BRD1 as a therapeutic target in rheumatoid arthritis Sci Rep. 2018 Jul 24;8(1):11125._x000D_ 8: Paternoster V, Edhager AV, Qvist P, Donskov JG, Shliaha P, Jensen ON, Mors O, Nielsen AL, Børglum AD, Palmfeldt J, Christensen JH. Inactivation of the Schizophrenia-associated BRD1 gene in Brain Causes Failure-to-thrive, Seizure Susceptibility and Abnormal Histone H3 Acetylation and N-tail Clipping Mol Neurobiol. 2021 Sep;58(9):4495-4505._x000D_ 9: Paternoster V, Svanborg M, Edhager AV, Rajkumar AP, Eickhardt EA, Pallesen J, Grove J, Qvist P, Fryland T, Wegener G, Nyengaard JR, Mors O, Palmfeldt J, Børglum AD, Christensen JH. Brain proteome changes in female Brd1(+/-) mice unmask dendritic spine pathology and show enrichment for schizophrenia risk Neurobiol Dis. 2019 Apr;124:479-488._x000D_ 10: Fryland T, Christensen JH, Pallesen J, Mattheisen M, Palmfeldt J, Bak M, Grove J, Demontis D, Blechingberg J, Ooi HS, Nyegaard M, Hauberg ME, Tommerup N, Gregersen N, Mors O, Corydon TJ, Nielsen AL, Børglum AD. Identification of the BRD1 interaction network and its impact on mental disorder risk Genome Med. 2016 May 3;8(1):53. _x000D_ _x000D_ Products Related to BRD1, GST-tag Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2019174 (50 μg)_x000D_ BRD1 (Bromodomain Containing 1) is a protein involved in gene regulation and chromatin remodeling. It contains bromodomains that recognize acetylated lysine residues, playing a crucial role in gene expression. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3