Recombinant Human JAK3 Protein (GST Tag, Active)

• Description:

  Recombinant Human JAK3 Protein (GST Tag, Active)_x000D_ Catalog number: B2018973_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5 µg_x000D_ Molecular Weight or Concentration: ~64 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: −80°C_x000D_ Keywords: JAK-3 Protein, Human; JAK3_HUMAN Protein, Human; JAKL Protein, Human; L-JAK Protein, Human; LJAK Protein, Human_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Deng H, Li H, Liu Z, Shen N, Dong N, Deng C, Liu F. Pro-osteogenic role of interleukin-22 in calcific aortic valve disease Atherosclerosis. 2024 Jan;388:117424._x000D_ 2: Meszaros EC, Malemud CJ. Phosphorylation of STAT proteins by recombinant human IL-6 in immortalized human chondrocyte cell lines, T/C28a2 and C28/I2 J Inflamm Res. 2017 Sep 28;10:143-150._x000D_ 3: Cheng H, Ross JA, Frost JA, Kirken RA. Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity Mol Cell Biol. 2008 Apr;28(7):2271-82._x000D_ 4: Cooper JE, Wiseman AC. Novel immunosuppressive agents in kidney transplantation Clin Nephrol. 2010 May;73(5):333-43._x000D_ 5: Gaspar HB, Gilmour KC, Jones AM. Severe combined immunodeficiency--molecular pathogenesis and diagnosis Arch Dis Child. 2001 Feb;84(2):169-73._x000D_ 6: Vadivel CK, Gluud M, Torres-Rusillo S, Boding L, Willerslev-Olsen A, Buus TB, Nielsen TK, Persson JL, Bonefeld CM, Geisler C, Krejsgaard T, Fuglsang AT, Odum N, Woetmann A. JAK3 Is Expressed in the Nucleus of Malignant T Cells in Cutaneous T Cell Lymphoma (CTCL) Cancers (Basel). 2021 Jan 14;13(2):280._x000D_ 7: Musso T, Johnston JA, Linnekin D, Varesio L, Rowe TK, O'Shea JJ, McVicar DW. Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7 J Exp Med. 1995 Apr 1;181(4):1425-31._x000D_ 8: Higuchi M, Kieff E, Izumi KM. The Epstein-Barr virus latent membrane protein 1 putative Janus kinase 3 (JAK3) binding domain does not mediate JAK3 association or activation in B-lymphoma or lymphoblastoid cell lines J Virol. 2002 Jan;76(1):455-9._x000D_ 9: Gires O, Kohlhuber F, Kilger E, Baumann M, Kieser A, Kaiser C, Zeidler R, Scheffer B, Ueffing M, Hammerschmidt W. Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins EMBO J. 1999 Jun 1;18(11):3064-73._x000D_ 10: Vainchenker W, Dusa A, Constantinescu SN. JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies Semin Cell Dev Biol. 2008 Aug;19(4):385-93. _x000D_ _x000D_ Products Related to Recombinant Human JAK3 Protein (GST Tag, Active) can be found at Proteins

• Short Description:

  Catalog Number: B2018973 (5 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3