IMB-10

• Description :

  IMB-10 is an αMβ2 integrin ligand. IMB-10 inhibits αMβ2-dependent migration and inflammation-induced neutrophil emigration[1].

• CAS Number :

  [307525-40-2]

• UNSPSC :

  12352005

• Hazard Statement :

  H411

• Target :

  Integrin

• Type :

  Reference compound

• Related Pathways :

  Cytoskeleton

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/imb-10.html

• Smiles :

  O=C1N(C(S/C1=C\C=C\C2=CC=CC=C2)=S)C3=CC=CC=C3C

• Molecular Formula :

  C19H15NOS2

• Molecular Weight :

  337.46

• Precautions :

  P273-P391-P501

• References & Citations :

  [1]Björklund M, et al. Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment. Biochemistry. 2006 Mar 7;45 (9) :2862-71.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported