IMB-10

• UNSPSC Description:

  IMB-10 is an αMβ2 integrin ligand. IMB-10 inhibits αMβ2-dependent migration and inflammation-induced neutrophil emigration[1].

• Target Antigen:

  Integrin

• Type:

  Reference compound

• Related Pathways:

  Cytoskeleton

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/imb-10.html

• Smiles:

  O=C1N(C(S/C1=C\C=C\C2=CC=CC=C2)=S)C3=CC=CC=C3C

• Molecular Weight:

  337.46

• References & Citations:

  [1]Björklund M, et al. Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment. Biochemistry. 2006 Mar 7;45(9):2862-71.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  307525-40-2