IMB-881

• Description :

  IMB-881 is an antibacterial agent. IMB-881 binds to LptA to inhibit the interaction between LptA and LptC. IMB-881 shows potent antibacterial activity against Gram-negative bacteria[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Bacterial

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  ClC(C1=CC=CN=C12)=CC3=C2OCN(CCC4=CC=CC=C4)C3

• Molecular Formula :

  C19H17ClN2O

• Molecular Weight :

  324.80

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Liu C, et al. Synthesis, biological evaluation and validation of IMB-881 derivatives as anti-Gram-negative bacterial agents. Bioorg Med Chem. 2025 Mar 1;119:118066. |[2]Zhang X, et al. Identification of an anti-Gram-negative bacteria agent disrupting the interaction between lipopolysaccharide transporters LptA and LptC. Int J Antimicrob Agents. 2019 Apr;53 (4) :442-448.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [501017-82-9]