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PXS-4728A

CAT: 0804-HY-112726-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112726-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PXS-4728A (BI-1467335) is a potent and orally active semicarbazide-sensitive amine oxidase (SSAO) inhibitor. PXS-4728A inhibits airway inflammation. PXS-4728A has the potential for the research of chronic obstructive pulmonary disease (COPD) [1].
CAS Number
1478364-68-9
Product Name Alternative
BI-1467335
UNSPSC
12352005
Hazard Statement
H302, H361, H373
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pxs-4728a.html
Purity
98.79
Solubility
DMSO : 233.33 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(NC(C)(C)C)C1=CC=C(OC/C(CN)=C/F)C=C1.Cl
Molecular Formula
C15H22ClFN2O2
Molecular Weight
316.80
Precautions
H302, H361, H373
References & Citations
[1]A G Jarnicki, et al. The Inhibitor of Semicarbazide-Sensitive Amine Oxidase, PXS-4728A, Ameliorates Key Features of Chronic Obstructive Pulmonary Disease in a Mouse Model. Br J Pharmacol. 2016 Nov;173 (22) :3161-3175.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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A16082-25BI 1467335 (PXS 4728A) 25mg
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A16082-1BI 1467335 (PXS 4728A) 1mg
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