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PXS-4787

CAT: 0804-HY-151498Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151498Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PXS-4787 is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively[1].
CAS Number
2409963-50-2
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pxs-4787.html
Solubility
DMSO : 25 mg/mL (ultrasonic; warming)
Smiles
NC/C=C(CS(=O)(C1=CC=CC=C1)=O)\F
Molecular Formula
C10H12FNO2S
Molecular Weight
229.27
References & Citations
[1]Chaudhari N, et al. Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis. Nat Commun. 2022 Sep 22;13 (1) :5555.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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