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PXS-6302

CAT: 0804-HY-151499Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151499Size:1 Each
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Description
PXS-6302 is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance[1].
CAS Number
2584947-54-4
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pxs-6302.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC/C=C(C(F)(S(=O)(C1=CC=CC=C1)=O)F)\F
Molecular Formula
C10H10F3NO2S
Molecular Weight
265.25
References & Citations
[1]Chaudhari N, et al. Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis. Nat Commun. 2022 Sep 22;13 (1) :5555.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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